CD46 CLIA Kit for Bovine(Bos taurus) | EIAab.comCD46 CLIA Kit for Bovine(Bos taurus)

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CD46 (Gene name),

Membrane cofactor protein (Protein name ), MCP_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CD46(MCP);

Protein name:

Membrane cofactor protein;

Alternative:

CD:

CD46;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with C3b and C4b.

Function:

Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. May act as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). In case of bovine viral diarrhea virus (BVDV) infection, involved in virus attachment to cells.

Subcellular Location:

Cytoplasmic vesicle secretory vesicle acrosome inner membrane Single-pass type I membrane protein Inner acrosomal membrane of spermatozoa.

Protein Attributes:

Sequence length:

361

Sequence:

50:

100:

150:

200:

250:

300:

350:

361:

ESHRQDILFS | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9913.ENSBTAP00000007108

KEGG:

bta:280851

String:

Q6VE48

Pfam:

PF00084

UniGene:

Bt.53657

Uniprot:

Q6VE48

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ELISA Kit for Bovine Membrane cofactor protein

Cat.:

E1275h

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96T

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ELISA Kit for Bovine Membrane cofactor protein

Cat.:

E1275b

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96T

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ELISA Kit for Bovine Membrane cofactor protein

Cat.:

E1275m

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96T

ELISA Kit for Bovine Membrane cofactor protein

Cat.:

E1275r

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96T

ELISA Kit for Bovine Membrane cofactor protein

Cat.:

E1275p

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96T

CLIA Kit for Bovine Membrane cofactor protein

Cat.:

U1275h

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Packing:

96T

CLIA Kit for Bovine Membrane cofactor protein

Cat.:

U1275m

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine Membrane cofactor protein

Cat.:

U1275r

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Membrane cofactor protein

Cat.:

U1275b

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Membrane cofactor protein

Cat.:

U1275p

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96T

Polyclonal Antibody for Bovine Membrane cofactor protein

Cat.:

P1275Rb-m

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40ug/0.2ml

Polyclonal Antibody for Bovine Membrane cofactor protein

Cat.:

P1275Rb-r

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40ug/0.2ml

Polyclonal Antibody for Bovine Membrane cofactor protein

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P1275Rb-h

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40ug/0.2ml

Monoclonal Antibody for Bovine Membrane cofactor protein

Protein for Bovine Membrane cofactor protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Subtractive expression cloning reveals high expression of CD46 at the blood-brain barrier."
Shusta E.V. , Zhu C. , Boado R.J. , Pardridge W.M.
J. Neuropathol. Exp. Neurol.61:597-604(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
tissue: Brain endothelium.
2.

"CD46 is a cellular receptor for bovine viral diarrhea virus."
Maurer K. , Krey T. , Moennig V. , Thiel H.-J. , Ruemenapf T.
J. Virol.78:1792-1799(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);PROTEIN SEQUENCE OF 49-69 AND 237-254;GLYCOSYLATION;TISSUE SPECIFICITY;INTERACTION WITH BOVINE VIRAL DIARRHEA VIRUS
tissue: Lymph node.

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